The only nominal association with diabetes incidence was found for the glucose-lowering allele at PROX1 (P = 0.02), in a direction opposite to that reported in case-control analyses in MAGIC, where the C allele increased type 2 diabetes risk (odds ratio 1.07 [95% CI 1.05–1.09], P = 7.2×10−10) [8]. The gene discussed is PROX1; the disease is diabetes mellitus.