The analysis involved age, sex, BMI, smoking, hypertension, diabetes and biochemical risk factors, including TC LDL-c, HDL-c, TG, SBP, DBP, fibrinogen, FPG, eGFR and cystatin C. As a result, serum cystatin C (odds ratio, OR = 1.326, 95% confidence interval(CI):1.086-1.619, P = 0.006), fibrinogen (OR = 1.629, 95% CI: 1.043-2.543, P = 0.032), FPG (OR = 1.363, 95% CI: 1.088-1.707, P = 0.007) and smoking (OR = 1.913, 95% CI: 1.007-3.633, P = 0.048) were independent predictors of the presence of the asymptomatic CAD. This evidence concerns the gene CST3 and hypertensive disorder.