PMEL and acute myeloid leukemia: 1I). This indicates the diagnosis of AML, so HMB-45 and Melan-A were added to stain and the result (HMB-45+, Melan-A+) demonstrated the diagnosis of AML. We searched the similar case on PubMed (http://www.ncbi.nlm.nih.gov) and found the inflammatory variant of AML may share the similar feature with our case, so the final diagnosis is hepatic inflammatory AML.