PNPLA3 and fatty liver disease: PNPLA3 148M allele was found associated with hepatic steatosis increased risk, although non-significant, in HCV genotype 2 (allelic Odds Ratio, O.R. = 2.3, 95 % Confidence Interval C.I. = 0.9-5.5, Padd = 0.053, Prec = 0.154, after adjustment for age, gender and BMI) and 3 (allelic O.R. = 1.7, 95 % C.I. = 0.9-3.4, Padd = 0.096, Prec = 0.991, after adjustment for age, gender and BMI) subjects.