PTPN22 and type 1 diabetes mellitus: Two of the remaining four, rs8052325 (CLEC16A) and rs1800521 (AIRE), are not in tight LD with known T1D SNPs (correlation coefficient ), while the final two, rs72650660 (CLEC16A) and rs3827734 (PTPN22), were not found by 1000 genomes presumably due to the small MAF (Table 2), which prevents us from calculating LD.