PTPN22 and type 1 diabetes mellitus: rs3184504 (SH2B3) and rs2476601 (PTPN22) are known T1D marker SNPs and rs28360489 (IL2RA) is in LD with a known T1D marker SNP (rs12722495, r2 = 0.62) (http://www.t1dbase.org/page/Regions).