In a previous investigation, we showed that loss of heterozygosity (LOH) of the Tg737 gene at markers SHGC-57879 and G64212 closely correlates with tumor node metastasis (TNM) stage and with HCC metastasis, indicating that these two markers can be detected independently and used to predict tumor stage and metastasis in HCC patients[7]. The gene discussed is IFT88; the disease is neoplasm.