Additional markers such as Caveolin-1, which was shown to be positive in 87% of chromophobe RCCs (20 of 23) and 0% of oncocytomas (0 of 8) and MOC-31, which was positive in 96% (22 of 23) of chromophobe RCCs and only 25% (2 of 8) of oncocytomas may also provide clinically important data (Lee et al., 2011). The gene discussed is CAV1; the disease is oncocytic adenoma.