ARR3 and lung cancer: Therefore, because Car-R mice are highly genetically different from the SWR/J line and are dominantly resistant to chemically induced skin and lung carcinogenesis, genetic analysis of the SWR/J x (SWR/J x Car-R) backcross population initially described in 2002 (Saran et al. 2002) should lead to the identification of genetic components providing resistance to skin and lung cancer phenotypes, segregated in specific small genomic regions.