Alzheimer's disease (AD) is defined by the appearance of pathological hallmarks within specific areas of the brain, including amyloid plaques, composed of extracellular amyloid beta (Aβ) peptide [1] and neurofibrillary tangles (NFTs), composed of intracellular aggregates of the microtubule-associated protein tau [2]. This evidence concerns the gene MAPT and Alzheimer disease.