Thus, in a multivariate model (which included TGFβ, IL-7, PSA, and Gleason Score) based on radical prostatectomy specimens, both TGFβ and IL-7 were independently predictive of prostate cancer survival, with hazard ratios of 10.4 and 0.1, respectively [15]. This evidence concerns the gene TGFB1 and Familial prostate cancer.