GPT and fibrosis: Multivariate analysis showed that necro-inflammation (OR: 1.506; 95% confidence interval (CI), 1.181–1.922, P = 0.001), steatosis (0 vs. >20%) (OR: 3.029; CI 1.154–7.951, P = 0.024), circulating estradiol levels (OR: 0.973, CI 0.947–0.999), P = 0.041), ALT (OR: 1.011, CI 0.003–1.019, P = 0.009) and portal vein diameter (OR: 2.644, CI 1.657–4.220, P<0.0001) were independently associated with the severity of fibrosis (Table 1).