CDKN1B and neoplasm: Our study of both nuclear levels and cytoplasmic mislocalization of p27Kip1 by H2O2 modulation contributes in some manner to the understanding of the potential prognostic and predictive value of the protein, as it was recently noted by Wender et al [57], since reduced nuclear p27Kip1 increases proliferation, and cytoplasmic p27Kip1 would drive tumor cell invasion.