As reported by Southam et al., in an allergic asthma murine model it has been shown that CD34+45+IL-5Rα+ cells, which are thought to be the earliest eosinophil lineage committed progenitor cell, give rise to eosinophil colonies only when isolated from the lungs of allergic but not control mice [47]. This evidence concerns the gene CD34 and allergic asthma.