However, in sharp contrast to the mouse model of DSS-induced colitis, the frequency of CD3+NKG2A+ cells in the lamina propria was significantly decreased in UC patients (4.44±1.57%) in comparison with HC and CD patients (8.68±4.73% and 10.49±3.33%, respectively; Figure 8B). The gene discussed is KLRC1; the disease is colitis.