As reported by Karonitsch et al., CXCL10 and CXCL9 mRNA expressions in monocytes were increased in SLE patients, associated with increased responsiveness of monocytes to IFN-γ, confirmed by mRNA levels of IFN-inducible STAT-1–dependent CXCL10 and CXCL9 genes [59]. This evidence concerns the gene IFNG and systemic lupus erythematosus.