CCL3 and Granuloma: The chemokines CCL3/MIP-1α, CCL4/MIP-1β, and CCL5/RANTES were highly elevated in AE patients [14], while mononuclear cells isolated from peri-parasite host granulomas secreted high amount of IL-10 and low amounts of IFN-γ disclosing an immune regulation which will counteract inflammatory responses in AE patients [15].