Cahill et al. (2006) identified a miRNA signature profile for a cPTC cell line that displays significant upregulaution of MIR141. In the present study, an investigation into the expression of MIR141 in a series of archival thyroid malignancies [cPTC, fvPTC, FTC, HT, or control (no evidence of disease or goiter tissues) tissues] was performed, with an aim to elucidating the expression MIR141 across subtypes of follicular thyroid neoplasia. Here, MIR141 is linked to goiter.