MLANA and infection: We have previously shown that mLANA is required for efficient replication in tissue culture following low MOI infection—the mLANA-null virus 73.Stop showed a 1- to 2-log defect in output virus from permissive fibroblasts upon low MOI infection (between 0.05 and 0.001 PFU/cell) compared to the genetically repaired 73.MR virus [27].