We observed a small but statistically insignificant difference between the AMD and control groups in the gender distribution according the levels of plasma CFH: men presented lower levels (612.9±164.4 μg/ml) than women (678.5±208.2 μg/ml) in the AMD group while in the control group, the opposite relationship was observed (men: 645.9±196.8 μg/ml; women: 619.9±174.8 μg/ml; Table 1). This evidence concerns the gene CFH and age-related macular degeneration.