IF1 overexpression is reported in human carcinomas [10], differences in the ratio of expression between IF1 and the F1Fo-ATPsynthase are related to changes in cellular responses to ischaemia/reperfusion injury [11, 12], and its absence is recorded in a rare form of mitochondrial myopathy called Luft's disease [13, 14]. This evidence concerns the gene ATP5IF1 and carcinoma.