Indeed, when we analyzed the clonotypic composition of NP-specific CD8+ T-cell populations 5 days after challenge with rVV-NP in mice infected with influenza 2 or 6 months previously, we observed that the TCR repertoire of each individual mouse was largely distinct, although some subdominant public TCRs were observed within time points (Supporting Information Table 1). Here, CD8A is linked to influenza.