FMR1 and polycystic ovary syndrome: The het-norm/low FMR1 sub-genotype, here again demonstrated to be very prominently present amongst African women (50.0% amongst donors and 23.5% amongst patients), has been associated with a polycystic ovary-like ovarian phenotype, at young age associated with excessive follicle recruitment and, therefore, rapid depletion in FOR, leading to DOR at relatively young ages [8].