Comparisons of BDNF immunostaining between sedentary and exercised stroke rats in cortical regions outside the lesion showed that exercise induced an increase in neuronal staining (Fig. 5, F1 vs F2) and the appearance of a strong BDNF staining of cerebral endothelium (Fig. 5, G1 vs G2). The gene discussed is BDNF; the disease is stroke disorder.