To corroborate the role of EZH2 and CTNNB1 in miR-214-mediated tumor cell invasion, we rescued the expression of EZH2 and CTNNB1 in miR-214 stable transfected HLE cells by transfecting a plasmid carrying wild-type EZH2 (pLVTHM-EZH2) [16] or CTNNB1 (pCI-CTNNB1, Addgene) [20]. Here, CTNNB1 is linked to neoplasm.