The aim of the current study was to build a q-PCR-based computational model able to preoperatively diagnose benign and malignant thyroid tumors on the basis of the expression profiles of the genes mentioned above (KIT, SYNGR2, C21orf4, Hs.296031, Hs.24183, CDH1, LSM7), plus two other genes (TC1, NATH) known to be involved in thyroid carcinogenesis from the literature [8-10]. This evidence concerns the gene KIT and thyroid cancer.