Amsterdam and Newberg [283] reported higher striatal DAT binding in the right posterior putamen and left caudate in a small number of patients with bipolar disorder; Chang and colleagues [284] reported that unmedicated euthymic subjects with bipolar disorder had significantly relatively higher whole striatal DAT binding; and Anand and colleagues [285] reported relatively lower DAT availability in the dorsal caudate nucleus (DCN) bilaterally. Here, SLC6A3 is linked to bipolar disorder.