It is noteworthy that the expression of proinflammatory cytokines detected in RVLM in this model of LPS-induced neurogenic hypertension is comparable to that found in the brain of other animal models of hypertension with neurogenic components, including chronic infusion of angiotensin II [7,14,46] and spontaneously hypertensive rats [5,10,12]. The gene discussed is AGT; the disease is Hypertension.