CLU and laryngotracheoesophageal cleft: The concentration of clusterin (mean ± SD) was 210.4 ± 61.3 μg/mL for HCC, 170.9 ± 50.0 μg/mL for LC, and 139.4 ± 37.4 μg/mL for normal subjects and was significantly higher in HCC than in LC (P < 0.01, Student's t-test) and in normal subjects (P < 0.001) (Figure 7).