In a multivariate model that included age, sex, BMI, hypertension, and serum lipids, adiponectin remained a significant predictor of eGFRMDRD (beta = −0.10,  P = 0.004) and eGFRCG (beta = −0.09, P = 0.001) as well as age (P < 0.0001) and serum lipids (P < 0.0001); this multivariate model explained 30% of the variation in eGFRMDRD (Table 3). The gene discussed is ADIPOQ; the disease is Hypertension.