Participants with moderate CKD (i.e., eGFR < 60 mL/min per 1.73 m2) were significantly older and had an elevated serum creatinine as well as serum adiponectin (based on MDRD: 8511.4 ng/mL versus 6760.8 ng/mL and based on CG: 8709.6 ng/mL versus 6606.9 ng/mL). This evidence concerns the gene ADIPOQ and chronic kidney disease.