Furthermore, adiponectin was significantly associated with moderate CKD regardless of the estimation method used to define moderate CKD (BMDRD = 1.61,  PMDRD = 0.006 and BCG = 1.90,  P < 0.0001, (Table 4)), and these associations are independent of the effects of serum lipids, age, and sex. The gene discussed is ADIPOQ; the disease is chronic kidney disease.