NFKB1 and acute respiratory distress syndrome: A recent study showed that the del/del genotype (patients homozygous for the 4 base pair deletion in the promoter of NFKB1) is associated with an age-dependent increase in odds of developing ARDS (OR 5.21, 95% CI 1.35–20.0) and patients with the del/del genotype and ARDS also have increased hazard of 60-day mortality (HR 1.54, 95% CI 1.01–2.36) and more organ failure (P < 0.001) [15].