Compared with patients with normal ABI, patients with ABI <0.9 were found to have an older age, higher prevalence of diabetes mellitus (DM), hypertension, coronary artery disease and cerebrovascular disease, lower prevalence of stage 3 CKD, lower diastolic blood pressure, higher pulse pressure, lower BMI, lower serum albumin, lower fasting glucose, lower hematocrit, lower eGFR, higher percentage of ACEI and/or ARB and non-ACEI/ARB antihypertensive drug use and higher LVMI (P = 0.009). The gene discussed is ALB; the disease is coronary artery disorder.