Additionally, these cells also express IL13Ra1 (Figure 4B), which is upregulated in GVHD, suggesting both that they are competent to respond to IL13, and as mentioned above, increased IL13Ra1 was associated with an IL13-driven expression signature in murine GVHD and human scleroderma [8]. This evidence concerns the gene IL13RA1 and scleroderma.