THSD4 and osteoporosis: When compared the results with the previous study, our SRC based variable selection method was able to locate osteoporosis susceptive genes that were reported before [19] such as ‘ESRRA’, ‘CALM1’, ‘CALM1’, ‘SPARC’,‘LRP1’, ‘THSD4’, ‘CRHR1’, ‘HSD11B1’, ‘THSD7A’, ‘BMPR1B’, ‘ADCY10’, ‘PRL’, ‘CA8’, et. al.Supporting Material S6 gives the first 50 gene expressions and SNPs selected using joint data sets.