Recently, 4-phenylcoumarins including mesuagenin C 3 from the species M. elegans have been shown to possess acetylcholinesterase (AChE) inhibitory activity [8] and cholinesterase inhibition has been proven to be one of the effective modes of treatment for Alzheimer's diseases [15]. This evidence concerns the gene ACHE and early-onset autosomal dominant Alzheimer disease.