The strength of the association between the two-allele haplotype of APOL1 variants rs60910145 and rs73885319 (G1) and non-diabetic CKD in the current study is about half of the sevenfold-increased odds of hypertensive kidney disease reported among African Americans carrying multiple copies of APOL1 risk alleles [10]. This evidence concerns the gene APOL1 and chronic kidney disease.