Recently, a region of chromosome 22, which includes APOL1 and MYH9 genes, was identified using mapping by admixture disequilibrium as a risk locus for non-diabetic forms of kidney disease, including idiopathic and HIV-associated focal segmental glomerular sclerosis (FSGS) and kidney disease clinically attributed to hypertension [7–9]. Here, APOL1 is linked to kidney disorder.