When comparing serum levels of CEA and IL-8 between all early stage (UICC stages I and II, n = 80) and late stage colon carcinomas (UICC stages III and IV, n = 84), the median serum level for CEA was 8.00 ng/mL in early stage and 47.97 ng/mL in late stage carcinomas (P = 0.0051). Here, CXCL8 is linked to carcinoma.