Finally, we measured both miR-421 and miR-30c levels in the plasma of 40 venous thrombosis patients including 20 patients with high (mean 40.50±13.05 UI/ml) and 20 patients with extremely low (mean 1.63±0.99 UI/ml) PAI-1 plasma levels. The gene discussed is SERPINE1; the disease is Venous thrombosis.