Additional studies with hR1 have found overexpression of IGF-1R, at a level comparable with that of RH-30, in other cancer cell lines, which include Capan-1 and BxPC-3 of pancreatic cancer, LNCaP of prostate cancer, Colo205 and HT-29 of colon cancer, HepG2 and Huh-7 of liver cancer, ACHN and 786-O of kidney cancer, SK-OV-4 of ovarian cancer, A375 of melanoma, A549 and SK-MES-1 of lung cancer, KMS11 of multiple myeloma, and RD of rhabdomyosarcoma (data not shown). The gene discussed is CDCA7L; the disease is AL amyloidosis.