CDCA7L and neoplasm: Likewise, in mice treated with the combination of Hex-hR1 and rapamycin, the average tumor volume, when measured on day 28, was significantly smaller (0.313±0.096 cm3) than in mice treated with only Hex-hR1 (1.162±0.276 cm3) or rapamycin (0.660±0.163 cm3), with P<0.029 (AUCday 28) for the combination vs. single agent.