JAK3 and severe combined immunodeficiency: In addition to inherited susceptibility to EV-HPV infections, an acquired form has been described in patients with HIV infection [18], [19], renal allograft transplant recipients [18], [20] and in patients undergoing chemotherapy [18], [21] or hematopoietic stem cell transplantation (HSCT) for severe combined immunodeficiency (SCID) caused by mutations in JAK3 or IL2RG, which encodes the common gamma chain (γc) [18], [22].