Several other genes involved in various functions, such as, hormonal response (AR, ESR1, ESR2, RARβ) cell cycle (CCND2, CDKN2A), tumor cell invasion (CAV1,CDH1,CDH13,LAMA3), and signal transduction (DAPK1, DAB2IP, RASSF1) are also affected by DNA hypermethylation in prostate cancer [27]. This evidence concerns the gene CDH1 and prostate cancer.