In order to rule out the possibility that expression of MIC-1/GDF15 by cancers in the TRAMP mice might impact upon tumor growth and modify differences between them and mice engineered to overexpress this cytokine, we quantified MIC-1/GDF15 expression in the prostate and seminal vesicle tumors from TRAMP and TRAMPfmsmic-1 mice. This evidence concerns the gene GDF15 and neoplasm.