CCND1 and familial pancreatic carcinoma: Second, NF-κB could promote pancreatic cancer growth due to its ability to inhibit cell apoptosis, induce mitogenic gene products (c-Myc and cyclin D1), increase expression of proangiogenic factor including vascular endothelial growth factor(VEGF), and promote the migration and invasion of pancreatic cancer cells [10], [11], [12], [13], [14].