Having previously shown that CD146+ breast tumors are mainly ER−PR− and that there is no correlation between the CD146 expression and the ErbB2 status [13], we quantified the transcripts encoding ER (α and β), PR and Erb receptors in MCF-7 cells over-expressing CD146 as compared to control MCF-7 cells (Fig. 2A). The gene discussed is ESR1; the disease is breast neoplasm.