The data from real-time RT-PCR assay indicate that hypoxia induced the relative levels of Nanog, Oct4 and EZH2 mRNAs as well as miR-21 and miR-210 in PC-3 and LNCaP cells whereas CDF decreased the levels of Nanog, Oct4 and EZH2 mRNAs as well as miR-21 and miR-210 in PCa cells under hypoxic condition (Figure 4). This evidence concerns the gene NANOG and posterior cortical atrophy.