When blood WAVE3 expression levels were compared among the patients with different SBR grade tumors, WAVE3 levels were the highest in the blood of patients with SBR3 compared to those patients with SBR1 tumors (p<2.2e−16), further confirming the association between WAVE3 expression levels and the tumor SBR grade that we originally derived from the results of the IHC staining analyses (Figure 6B). The gene discussed is WASF3; the disease is neoplasm.