CDH13 and depressive disorder: In addition, CDH13 has also been implicated by GWAS in depression (rs10514585) [68], extraversion (rs4783307, rs8056579) [69], agreeableness (rs9940706) [69] and response to antipsychotic therapy (rs17216786) [70], as well as in a meta-analysis for extraversion (rs8057458) [71].