We thus repeated our analyses in this region, testing for association of type 1 diabetes with rare variants within MHC genes after adjustment for the lead GWAS SNP (rs9268645) [Barrett et al., 2009, with genotypes coded by the number of minor alleles, included as an additional covariate in the logistic regression model (Table 1 and Figure 4). The gene discussed is HLA-C; the disease is type 1 diabetes mellitus.