TGFBI and ovarian carcinoma: Our data, showing high levels of βig-H3 immunostaining in normal ovarian surface epithelial cells (Figure 2a) and benign serous ovarian tumors (Figure 2b) but low βig-H3 immunostaining in human serous ovarian cancer cells (Figure 2c), suggest that βig-H3 is down-regulated during the process of ovarian cancer tumorigenesis [61].