PAX2 and renal fibrosis: Huang et al. [47] explored the potential role of PAX2 in EMT that was induced in the remnant kidney of rats following 5/6 nephrectomy, and also examined PAX2 in cultured renal tubular epithelial cells, and their interesting experiments suggest that the re-expression of PAX2 in the tubular epithelial cells played an important role in the promotion of EMT, and there might a therapeutic value in silencing PAX2 to prevent or reverse renal fibrosis.