Recently, our research group has described that the 3,5-dimethoxyphenyl and 4-cyanophenyl methylseleno imidocarbamates (Figure 2) in the prostate cancer cell (PC-3) caused an important inhibitory effect in Akt and ERK phosphorylation, two key nodes in PI3K and mitogen activated protein kinase (MAPK) pathways, respectively. The gene discussed is AKT1; the disease is prostate cancer.